Pyridostigmine prevents haemodynamic alterations but does not affect their nycthemeral oscillations in infarcted mice

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Pyridostigmine prevents haemodynamic alterations but does not affect their nycthemeral oscillations in infarcted mice

The increase in acetylcholine yielded by pyridostigmine (PYR), an acetylcholinesterase inhibitor, was evaluated for its effect on the haemodynamic responses-mean arterial pressure (MAP) and heart rate (HR)-and their nycthemeral oscillation in mice before and one week after myocardial infarction (MI). Mice were anesthetized (isoflurane), and a telemetry transmitter was implanted into the carotid...

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ژورنال

عنوان ژورنال: Autonomic Neuroscience

سال: 2015

ISSN: 1566-0702

DOI: 10.1016/j.autneu.2014.11.007